FSH Society funded researchers at Nationwide Children’s Hospital have a monthly podcast series entitled “This Month in Muscular Dystrophy”. February’s podcast is on DUX4 as a Potential Candidate Gene for Facioscapulohumeral Muscular Dystrophy. Dr. Kevin Flanigan interviews Dr. Scott Harper at Nationwide Children's Hospital about DUX4 as a Potential
Candidate Gene for Facioscapulohumeral Muscular Dystrophy (FSHD). FSHD patients and their families should be aware of the following educational and informative Podcast on FSHD, D4Z4, DUX4, AAV and P53. About 20 minutes in length it is very informative for those wishing a lay audience level discussion of recent advances in our understanding of FSHD.
Nationwide Children's Hospital
"This Month in Muscular Dystrophy"
Podcasts Dedicated to the Latest Neuromuscular Research
Hosted by Kevin Flanigan, MD, "This Month in Muscular Dystrophy" podcasts highlight the latest in muscular dystrophy and other inherited neuromuscular disease research. During each podcast, authors of recent publications discuss how their work improves o ur understanding of inherited neuromuscular diseases, and what their work might mean for treatment of these diseases.
Featured Podcasts
February 2011: Dr. Scott Harper Discusses DUX4 as a Potential Candidate Gene for Facioscapulohumeral Muscular Dystrophy.
Click HERE to listen to the Podcast
This was initiated and supported by several FSH Society fellowship grants. The acknowledgements in the paper are as follows:
“Acknowledgments
This work was financially supported by the Facioscapulohumeral Society Landsman Charitable Trust Research Fellowship Grant (FSHD-LCT-002, to S.Q.H.) and Conners and Jacobs Families Research Fellowship Grant (FSHS-JJFR-001, to S.Q.H.), and a National Institutes of Health (NIH) KL2 Clinical and Translational Scholar Award (KL2 RR025754, to S.Q.H.). Additional support was provided by startup funds to S.Q.H. and a Graduate Student Fellowship to L.M.W. from the Research Institute at Nationwide Children’s Hospital Research Foundation.
We thank members of the Harper laboratory for assistance and support, Dr. S. Hauschka for providing the MHCK7 promoter, Dr. P. Martin for Trp53 mice, Dr. Yi-Wen Chen for DUX4 antibodies, Mr. D. P. Perez for advice and support, and Dr. K. R. Clark and TRINCH Viral Vector Core Facility members for assistance with AAV production.”
Listen to this Podcast
Guest: Scott Harper, Ph.D., Nationwide Children's Hospital
Access an abstract of this Month's Featured Research Article: DUX4, a candidate gene for facioscapulohumeral muscular dystrophy, causes p53-dependent myopathy in vivo. Ann Neurol. 2010 Oct 28. [Epub ahead of print].
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